Calendula Sun-Infused Salve: Faradiol Monoesters & Granulation Tissue

The Golden Marigold of Mediterranean Gardens

1. Faradiol Triterpenoid Monoesters: The primary anti-inflammatory principles of calendula are faradiol monoesters (faradiol myristate, faradiol palmitate). In standardized cutaneous edema models, faradiol exhibits anti-inflammatory potency equivalent to indomethacin.
2. Accelerating Granulation & Angiogenesis: Calendula extracts upregulate basic fibroblast growth factor (bFGF), accelerating the deposition of healthy Type I and III collagen fibrils and promoting new capillary budding.

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Primary Scientific Citations

1. Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.
2. Zitterl-Eglseer, K., et al. (1997). Anti-oedematous activities of the main triterpendiol esters of marigold (Calendula officinalis L.). Journal of Ethnopharmacology, 57(2), 139-144.